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Antihistamines and Prostate Cancer / Antihistamine Alternatives for Hay fever

edited from a post on pralt-discuss

Thanks to Taras and Ralph, for these citations and alternatives for hay fever.
Larry Clapp

Antihistamines (AHs) are definitely a no no for individuals with BPH. They restrict urinary flow. As a matter of fact, some surgery patients are prescribed AHs to stop the "dribbles".

On the other hand you are partially correct in your mention about AHs and cancer. Some Canadian studies by Lorne J. Brandes were published in the Sept 1994 of Scientific American. The bottom line, is that in animal studies, both AHs and antidepressants are involved in binding to receptors in the family of enzymes known as cytochrome-P450 resulting in tumor growth.

The problem as Brandes sees it is in the tumor cell promotion at low to medium doses rather than at the expected high doses. You can also search Medline for Brandes LJ and read some of the citations on antihistamines and cytochrome-P450 promotion of tumor growth.

You know that I am not a doctor, but I am going to suggest that you try the following: Buy some grape seed antioxidant at Trader Joe's. Start taking one mg for each pound of body weight. This can go for a few weeks until you notice an improvement. When you do, start cutting back slowly. Let's say that you are 200 lbs and are taking 200 mg. Cut back to 150 mg. If the hay fever returns, go back to the original dose. If it doesn't after a while cut back to 100 mg as a maintenance dose.

I find that this regimen works well for me. A bottle of 250 caps (50 mg) I believe is about $20. Try it and see if it works for you. I never had a severe case myself, but I used to take antihistamines a good part of the year. Forgot to tell you. Space them throughout the day. Two in the am, and then one at lunch and another one at dinner.